Mentor/s:
Carmen S. Maldonado, PhD
Project Title:
Predictive Modeling of Hippocampal-Dependent Learning and Memory under LPS-Induced Neuroinflammation and URB597-Mediated Endocannabinoid Modulation
Project Description:
This project investigates how neuroinflammation induced by lipopolysaccharide (LPS) affects hippocampal-dependent cognitive functions, specifically learning and memory. Utilizing a pharmacological approach with URB597 to enhance endocannabinoid signaling, the study aims to counteract inflammation-driven cognitive deficits. Behavioral data from spatial memory and object recognition tasks, along with hippocampal CB1 receptor expression, are integrated into a computational predictive model to forecast cognitive outcomes under inflammatory conditions.
Mentor/s:
Edward Awh, PhD
Project Title:
Enhancing Working Memory Performance Via Long-term Memory Utilization
Project Description:
The project at the University of Chicago with Dr. Edward Awh involved developing and analyzing behavioral tasks to assess how the utilization of long-term memory strategies could enhance working memory performance. Human subjects performed dual-task experiments designed specifically to reveal underlying cognitive mechanisms, with the data analyzed using Python-based statistical tools, NumPy, and Pandas for robust interpretation.
